the mechanisms of radiation-induced bystander effect

Authors

m najafi department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran

r fardid department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran

gh hadadi department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran

m fardid health management and economics research center, iran university of medical science, tehran, iran.

abstract

the radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. these changes are confirmed by results of some in-vivo studies. most well-known important factors affecting radiation-induced bystander effect include free radicals, immune system factors, expression changes of some genes involved in inflammation pathway and epigenetic factors.

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Journal title:
journal of biomedical physics and engineering

جلد ۴، شماره ۴ DEC، صفحات ۰-۰

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